Analysis of proliferating potential by argyrophilic nucleolar organizer regions (AgNORs) and proliferating cell nuclear antigen (PCNA) staining in experimental pancreatic ductal carcinoma in dogs.

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Comparison of Argyrophilic Nucleolar Organiser Regions (AgNORS) with Proliferating Cell Nuclear Antigen (PCNA) in Different Grades of Transitional Cell Carcinoma of Urinary Bladder

Malignancies of urinary bladder are one of the leading malignancies in the developed countries. 1 The incidence is also high in Northern Africa and Western Asia. The world wide estimate of carcinoma of urinary bladder of new cases is 261,000 annually. 2 Amongst these, more than 50,000 cases and estimate of 9500 deaths have been predicted in United States alone. 3 The incidence is three times mo...

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[Clinical significance of proliferating cell nuclear antigen (PCNA) and argyrophilic nucleolar organizer region (AgNOR) in testicular tumors].

BACKGROUND Proliferative potential of testicular tumor was assessed by immunohistochemistry using anti-proliferating cell nuclear antigen (PCNA) monoclonal antibody and silver staining of argyrophilic nucleolar organizer region (AgNOR), and the results were compared with clinical course. METHODS Fourty-five patients with testicular tumor and 10 normal testicles were investigated. All specimen...

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Proliferating cell nuclear antigen (PCNA) and nucleolar organiser regions in Hodgkin's disease: correlation with morphology.

AIM To define the distribution of proliferating cell nuclear antigen (PCNA) and silver staining nucleolar organiser regions (AgNORs) in Hodgkin's disease. METHODS PCNA was shown in a series of 34 cases of Hodgkin's disease using immunohistochemical methods. In a second series of 46 cases the AgNOR technique for interphase nucleolar organiser regions was studied. Both series comprised routinel...

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Proliferating Cell Nuclear Antigen (PCNA) in Prostatic Carcinoma

Proliferating cell nuclear antigen (PCNA) is an auxiliary protein of DNA • @polymerase-• Ý • @ that • @is • @ synthesized • @ during • @ the • @ late • @G1 • @ phase through the S phase of cell proliferation. The expression of PCNA correlates strongly with cell proliferation. In the present study, employing NC-012, which is an anti-human PCNA monoclonal antibody, we performed immunohistochemica...

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Prognostic significance of argyrophilic nucleolar organizer regions in esophageal carcinoma.

The argyrophilic nucleolar organizer region (AgNOR) of 100 cancer cells from biopsy specimens of esophageal squamous cell carcinomas in 98 surgically treated cases was examined, using a silver colloid staining technique on biopsy specimens. The number of AgNOR per nucleus (AgNOR number) was higher in the more advanced groups with regard to the length of the tumor (P less than 0.01), the depth o...

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ژورنال

عنوان ژورنال: Juntendo Medical Journal

سال: 1996

ISSN: 0022-6769,2188-2134

DOI: 10.14789/pjmj.42.368